UNIVERSIDADE FEDERAL DO PARÁ INSTITUTO DE CIÊNCIAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS FARMACÊUTICAS MEDICAMENTOS UTILIZADOS NO CONTROLE DA HIPERTENSÃO NO DISTRITO ADMINISTRATIVO DAGUA EM BELÉM, PA. Autor: Luiz Mário Pará Rodrigues Orientadora: Profa. Dra. Marcieni Andrade Coorientador: Prof. Dr. Marcos Silva
Smoking - the facts
Smoking - The Facts
Cigarette smoking is the greatest single cause of il ness and premature death in the UK. This leafletgives reasons why smoking is so harmful. It also lists the benefits of stopping, and where to go forhelp.
Some initial facts and figures About 100,000 people in the UK die each year due to smoking. Smoking-related deaths are mainly due tocancers, chronic obstructive pulmonary disease (COPD) and heart disease.
About half of all smokers die from smoking-related diseases. If you are a long-term smoker, on average, your lifeexpectancy is about 10 years less than a non-smoker. Put another way, in the UK about 8 in 10 non-smokers livepast the age of 70, but only about half of long-term smokers live past 70. The younger you are when you startsmoking, the more likely you are to smoke for longer and to die early from smoking.
Many smoking-related deaths are not quick deaths. For example, if you develop COPD you can expect severalyears of illness and distressing symptoms before you die.
Smoking increases the risk of developing a number of other diseases (listed below). Many of these may not befatal, but they can cause years of unpleasant symptoms.
The good news is:
Stopping smoking can make a big difference to your health. It is never too late to stop smoking togreatly benefit your health. For example, if you stop smoking in middle age, before having cancer orsome other serious disease, you avoid most of the increased risk of death due to smoking.
Many people have given up smoking. In 1972 just under half of adults in the UK were smokers. By1990 this had fallen to just under a third. At present, about a sixth of UK adults are smokers.
Help is available if you want to stop smoking but are finding it difficult.
Cigarette smoke contains the following Nicotine
Nicotine is a drug that stimulates the brain. If you are a regular smoker, when the blood level of nicotine falls, you
usually develop withdrawal symptoms, such as craving, anxiety, restlessness, headaches, irritability, hunger,
difficulty with concentration, or just feeling awful. These symptoms are relieved by the next cigarette.
So, most smokers need to smoke regularly to feel normal, and to prevent nicotine withdrawal symptoms.
Tar which contains many chemicals
These deposit in the lungs and can get into the blood vessels and be carried to other parts of the body. Cigarette
smoke contains over 4,000 chemicals, including over 50 known carcinogens (causes of cancer) and other
This chemical affects the oxygen-carrying capacity of the blood. In particular, in pregnant women who smoke, this
causes a reduced amount of oxygen to get to the growing baby. This is thought to be the most important cause
for the bad effects of smoking on the growing baby.
Which diseases are caused or made worse by smoking? Lung cancer. About 30,000 people in the UK die from lung cancer each year. More than 8 in 10 cases
are directly related to smoking.
Chronic obstructive pulmonary disease (COPD). About 25,000 people in the UK die each year
from this serious lung disease. More than 8 in 10 of these deaths are directly linked to smoking.
People who die of COPD are usually quite unwell for several years before they die.
Heart disease. This is the biggest killer illness in the UK. About 120,000 people in the UK die each
year from heart disease. About 1 in 6 of these is due to smoking.
Other cancers - of the mouth, nose, throat, larynx, gullet (oesophagus), pancreas, bladder, cervix,
blood (leukaemia), and kidney are all more common in smokers.
Circulation. The chemicals in tobacco can damage the lining of the blood vessels and affect the level
of lipids (fats) in the bloodstream. This increases the risk of atheroma forming (sometimes called
hardening of the arteries). Atheroma is the main cause of heart disease, strokes, peripheral vascular
disease (poor circulation of the legs), and aneurysms (swollen arteries which can burst causing
internal bleeding). All of these atheroma-related diseases are more common in smokers.
Sexual problems. Smokers are more likely than non-smokers to become impotent or have difficulty in
maintaining an erection in middle life. This is thought to be due to smoking-related damage of the the
blood vessels to the penis.
Rheumatoid arthritis. Smoking is known to be a risk factor for developing rheumatoid arthritis. One
research study estimated that smoking is responsible for about 1 in 5 cases of rheumatoid arthritis.
Ageing. Smokers tend to develop more lines on their face at an earlier age than non-smokers. This
often makes smokers look older than they really are.
Fertility is reduced in smokers (both male and female).
Menopause. On average, women who smoke have a menopause nearly two years earlier than non-
Other conditions where smoking often causes worse symptoms include: asthma, colds, flu,
chest infections, tuberculosis, chronic rhinitis, diabetic retinopathy, hyperthyroidism, multiple sclerosis,
optic neuritis, and Crohn's disease.
Smoking increases the risk of developing various other conditions including: dementia, optic
neuropathy, cataracts, macular degeneration, pulmonary fibrosis, psoriasis, gum disease, tooth loss,
osteoporosis and Raynaud's phenomenon.
Smoking in pregnancy increases the risk of: Miscarriage.
Complications of pregnancy, including bleeding during pregnancy, detachment of the placenta,premature birth, and ectopic pregnancy.
Low birthweight. Babies born to women who smoke are on average 200 grams (8 oz) lighter thanbabies born to comparable non-smoking mothers. Premature and low birthweight babies are moreprone to illness and infections.
Congenital defects in the baby - such as cleft palate.
Stillbirth or death within the first week of life - the risk is increased by about one-third.
Poorer growth, development, and health of the child. On average, compared with children born to non-smokers, children born to smokers are smaller, have lower achievements in reading and maths, andan increased risk of developing asthma.
How does smoking affect other people? Children
Children and babies who live in a home where there is a smoker:
Are more prone to asthma and ear, nose and chest infections. About 17,000 children under five yearsold in England and Wales are admitted to hospital each year due to illnesses caused by their parents'smoking.
Have an increased risk of dying from cot death (sudden infant death syndrome).
Are more likely than average to become smokers themselves when older.
On average, do less well at reading and reasoning skills compared with children in smoke-free homes,even at low levels of smoke exposure.
Are at increased risk of developing COPD and cancer as adults.
Passive smoking of adults
You have an increased risk of lung cancer and heart disease if you are exposed to other people smoking for long
periods of time. Tobacco smoke is also an irritant, and can make asthma and other conditions worse.
Other problems with smoking Your breath, clothes, hair, skin, and home smell of stale tobacco. You do not notice the smell if yousmoke, but to non-smokers the smell is obvious and unpleasant.
Your sense of taste and smell are dulled. Enjoyment of food may be reduced.
Smoking is expensive.
Life insurance is more expensive.
Finding a job may be more difficult as employers know that smokers are more likely than non-smokersto have sick leave. More than 34 million working days (1% of total) are lost each year because ofsmoking-related sick leave.
Potential friendships and romances may be at risk. (Smoking is not the attractive thing that cigaretteadvertisers portray.) What are the benefits of stopping smoking? The benefits begin straight away. You reduce your risk of getting serious disease no matter what age you give up.
However, the sooner you stop, the greater the reduction in your risk.
If you have smoked since being a teenager or young adult: If you stop smoking before the age of about 35, your life expectancy is only slightly less than peoplewho have never smoked.
If you stop smoking before the age of 50, you decrease the risk of dying from smoking-relateddiseases by 50%.
But, it is never too late to stop smoking to gain health benefits. Even if you already have COPD or heart disease,your outlook (prognosis) is much improved if you stop smoking.
Timeline of health benefits after stopping smoking .
Health Benefit .
Breathing becomes easier. Bronchial tubes begin to relax and energy levels increase.
Skin appearance improves, owing to improved skin perfusion.
Cough, wheezing, and breathing problems improve and lung function increases by up to 10%.
Risk of a heart attack falls to about half that of a smoker.
Risk of lung cancer falls to about half that of a smoker.
Risk of heart attack falls to the same level that it would be for someone who has never smoked.
Other benefits of stopping smoking include the following: Chest infections and colds become less frequent.
The smell of stale tobacco goes from your breath, clothes, hair, and face.
Foods and drinks taste and smell much better.
Finances improve. You will save well over £1,000 per year if you smoked 20 a day.
You are likely to feel good about yourself.
How can I stop smoking? About 2 in 3 smokers want to stop smoking. Some people can give up easily. Willpower and determination arethe most important aspects when giving up smoking. However, nicotine is a drug of addiction and many peoplefind giving up a struggle. Help is available: GPs, practice nurses, or pharmacists can provide information, encouragement, and tips on stoppingsmoking. Also, throughout the country there are specialist NHS Stop Smoking Clinics which have agood success in helping people to stop smoking. Your doctor may refer you to one if you are keen tostop smoking.
Various medicines can increase your chance of quitting. These include Nicotine Replacement Therapy(NRT) which comes as gums, sprays, patches, tablets, lozenges, and inhalers. You can buy NRTwithout a prescription. Also, medicines called bupropion (trade name Zyban®) and varenicline (trade Further help & information 6th floor, Suites 59-63, New House, 67-68 Hatton Garden, London, EC1N 8JY Tel: 0207 404 0242 20-22 Curtain Road, London, EC2A 3NF Tel: (Quitline) 0800 002200, (Admin) 0207 539 1700 Further reading & references , NICE (2006), Action on Smoking and Health (various dates) Prodigy (April 2008); Smoking is a major preventable risk factor for rheumatoid arthritis: estimations AnnRheum Dis. 2011 Mar;70(3):508-11. Epub 2010 Dec 13.
; Heavy Smoking in Midlife and Long-term Risk of Alzheimer Disease andVascular Arch Intern Med. 2011 Feb 28;171(4):333-9. Epub 2010 Oct 25.
Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical
conditions. EMIS has used all reasonable care in compiling the information but make no warranty as to its
accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions.
For details see our.
Dr Beverley Kenny View this article online at Discuss Smoking - The Facts and find more trusted resources at EMIS is a trading name of Egton Medical Information Systems Limited.
For Healthcare Professional use Toddler Factsheet 4.5 from tooth decay The first teeth usually start to erupt at around six All drinks should be taken from a cup or glass, not a months and are all through by three years. Dental caries (tooth decay) is a softening of the Tooth brushing should begin once the child's first